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NICE guidance emphasises that pharmacological interventions should be part of a multicomponent approach that includes dietary modification, increased physical activity, and behavioural strategies for optimal and sustainable outcomes

The most well-known is orlistat , available as Xenical (prescription) and Alli (over-the-counter)

Eli Lilly made a similar statement: FDA was also clear that compounders must immediately begin transitioning patients taking compounded tirzepatide knockoffs to FDA-approved tirzepatide medicines. However, both companies have a big financial interest in limiting the sales of compounded GLP-1s

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